Bacognize Extract Clinical and Preclinical Research
In randomized, placebo controlled, crossover human trial, administration of a proprietary extract of Bacopa monnieri (BACOGNIZE, 300mg/day) to medical students significantly improved (p<0.05) several parameters of cognitive function, including memory, focus and attention (see fig.1).(1)
In randomized, placebo controlled, crossover human trial, administration of a proprietary extract of Bacopa monnieri (BACOGNIZE, 300mg/day) to medical students significantly improved (p<0.05) several parameters of cognitive function, including memory, focus and attention (see fig.1).(1) In another randomized, placebo controlled trial in older adults, positive trends in working memory, attention and focus were seen in the BACOGNIZE group (300mg/day) compared to placebo.(2)
An open trial of BACOGNIZE in elderly adults also showed statistically significant results (p<0.001) in scores on attention and language compared to baseline.(3)
Pharmacology research on BACOGNIZEŽ and its isolated constituents showed strong regulation at serotonin receptors that are key for higher cognitive functions such as memory, mood and focus.(4)
| 1. | Kumar et al. Effects of Bacopa monnieri (BACOGNIZE) on memory in medical students. Manuscript. |
| 2. | Headapohl et al. Effects of Bacopa monnieri (BACOGNIZE) on memory and cognitive function in healthy older adults: A double-blind placebo-controlled study. Manuscript |
| 3. | Shishir et al. Open trial of Bacopa monnieri (BACOGNIZE) in elderly adults with low MMSE scores. Manuscript. |
| 4. | Pharmacology of Bacopa monnieri (BACOGNIZE) at 5HT1a and 5HT2a receptors. Presented at 2005 Annual Meeting of the American Society of Pharmacognosy, Corvallis, Oregon |




